"(Diet drugs) can be safe in the short run only," said Dr. Stanley Hodges, medical director of hospital internal medicine associates at Indian Path Medical Center. "I prefer them not to be used any longer than an eight-week period of time. Anorexiants (one category of diet drug that diminishes appetite) have a tendency to cause elevation in blood pressure, increase your risk of heart attack and stroke. ... The long-term effects are not good, as far as what it does to your health. When should they be used? They should be used as a last resort."
--Losing Proposition: Weight Loss Drugs Should Be Last Resort